J.B. Baell: search on Z-Library

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1

Seven Year Itch. Pan-Assay Interference Compounds (PAINS) in 2017 - utility and limitations

Baell, Jonathan B., Nissink, J. Willem M.

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 409 KB

english, 2017

2

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Baell, Jonathan B., Holloway, Georgina A.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.67 MB

english, 2010

3

Chemistry: Chemical con artists foil drug discovery

Baell, Jonathan, Walters, Michael A.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.87 MB

english, 2014

4

Reviewing hit discovery literature for difficult targets: glutathione transferase omega-1 as an example

Xie, Yiyue, Dahlin, Jayme L., Oakley, Aaron J, Casarotto, Marco G., Board, Philip G., Baell, Jonathan B.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

5

Contemporary anti-Ebola drug discovery approaches and platforms

Schneider-Futschik, Elena K., Hoyer, Daniel, Khromykh, Alex, Baell, Jonathan B., Marsh, Glenn, Baker, Mark A., Li, Jian, Velkov, Tony

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 769 KB

english, 2018

6

KNIME Workflow to Assess PAINS Filters in SMARTS Format. Comparison of RDKit and Indigo Cheminformatics Libraries

Simon Saubern, Rajarshi Guha, Jonathan B. Baell

Journal:

Molecular Informatics

Year:

2011

Language:

english

File:

PDF, 508 KB

english, 2011

7

Comunidades sordas: ¿pacientes o ciudadanas?

Irma M. Muñoz-Baell, María Teresa Ruiz-Cantero, Carlos Álvarez-Dardet, Emilio Ferreiro-Lago, Eva Aroca-Fernández

Journal:

Gaceta Sanitaria

Year:

2011

File:

PDF, 129 KB

2011

8

Contents

Brady, Ryan M., Zhang, Minmin, Gable, Robert, Norton, Raymond S., Baell, Jonathan B.

Journal:

Clinics in Podiatric Medicine and Surgery

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

9

1,2,4-Oxadiazole antimicrobials act synergistically with daptomycin and display rapid kill kinetics against MDR Enterococcus faecium

Carter, Glen P, Harjani, Jitendra R, Li, Lucy, Pitcher, Noel P, Nong, Yi, Riley, Thomas V, Williamson, Deborah A, Stinear, Timothy P, Baell, Jonathan B, Howden, Benjamin P

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2018

Language:

english

File:

PDF, 674 KB

english, 2018

10

Polypeptide ω-conotoxin GVIA as a basis for new analgesic and neuroprotective agents

Raymond S. Norton, Paul K. Pallaghy, Jonathan B. Baell, Christine E. Wright, Michael J. Lew, James A. Angus

Journal:

Drug Development Research

Year:

1999

Language:

english

File:

PDF, 270 KB

english, 1999

11

ω-Conotoxins and Approaches to Their Non-Peptide Mimetics.

Jonathan B. Baell, Peter J. Duggan, Y. Phei Lok

Journal:

Year:

2004

File:

PDF, 54 KB

2004

12

ChemInform Abstract: Discovery of Novel and Potent Benzhydryl-Tropane Trypanocides Highly Selective for Trypanosoma cruzi.

G. A. Holloway, J. P. Parisot, P. M. Novello, K. G. Watson, T. Armstrong, R. C. A. Thompson, I. P. Street, J. B. Baell

Journal:

Year:

2010

File:

PDF, 19 KB

2010

13

ChemInform Abstract: Benzoylureas as Removable cis Amide Inducers: Synthesis of Cyclic Amides via Ring Closing Metathesis (RCM).

Ryan M. Brady, Yelena Khakham, Guillaume Lessene, Jonathan B. Baell

Journal:

Year:

2011

Language:

english

File:

PDF, 34 KB

english, 2011

14

Synthesis and biological evaluation of nonpeptide mimetics of ω-conotoxin GVIA

Jonathan B Baell, Peter J Duggan, Stewart A Forsyth, Richard J Lewis, Y Phei Lok, Christina I Schroeder

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 441 KB

english, 2004

15

A three-residue, continuous binding epitope peptidomimetic of ShK toxin as a Kv1.3 inhibitor

Andrew J. Harvey, Robert W. Gable, Jonathan B. Baell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 213 KB

english, 2005

16

Synthesis and biological evaluation of chalcones as inhibitors of the voltage-gated potassium channel Kv1.3

Julia Cianci, Jonathan B. Baell, Bernard L. Flynn, Robert W., Gable, Jorgen A. Mould, Dharam Paul, Andrew J. Harvey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 562 KB

english, 2008

17

Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi

G.A. Holloway, J.P. Parisot, P.M. Novello, K.G. Watson, T. Armstrong, R.C.A. Thompson, I.P. Street, J.B. Baell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

18

Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines

Duong Nhu, Sandra Duffy, Vicky M. Avery, Andrew Hughes, Jonathan B. Baell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 352 KB

english, 2010

19

3-Alkylthio-1,2,4-triazine dimers with potent antimalarial activity

Kung Ban, Sandra Duffy, Yelena Khakham, Vicky M. Avery, Andrew Hughes, Oliver Montagnat, Kasiram Katneni, Eileen Ryan, Jonathan B. Baell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 837 KB

english, 2010

20

Synthesis and biological evaluation of anthranilamide-based non-peptide mimetics of ω-conotoxin GVIA

Jonathan B. Baell, Peter J. Duggan, Stewart A. Forsyth, Richard J. Lewis, Y. Phei Lok, Christina I. Schroeder, Nicholas E. Shepherd

Journal:

Year:

2006

Language:

english

File:

PDF, 275 KB

english, 2006

21

Synthesis, reactivity and applications of 1-fluoroalkyl carboxylates: novel synthetic substrates for esterases and lipases

Carl S. Rye, Jonathan B. Baell, Ian Street

Journal:

Year:

2007

Language:

english

File:

PDF, 627 KB

english, 2007

22

Microwave-assisted, zinc-mediated peptide coupling of N-benzyl-α,α-disubstituted amino acids

Julia Cianci, Jonathan B. Baell, Andrew J. Harvey

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 107 KB

english, 2007

23

ω-Conotoxin GVIA mimetics based on an anthranilamide core: Effect of variation in ammonium side chain lengths and incorporation of fluorine

Asa Andersson, Jonathan B. Baell, Peter J. Duggan, Janease E. Graham, Richard J. Lewis, Natalie G. Lumsden, C. Elisabet Tranberg, Kellie L. Tuck, Aijun Yang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 462 KB

english, 2009

24

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

Georgina A. Holloway, Jonathan B. Baell, Alan H. Fairlamb, Patrizia M. Novello, John P. Parisot, John Richardson, Keith G. Watson, Ian P. Street

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 202 KB

english, 2007

25

Effects of modulators of Ca2+-activated, intermediate-conductance potassium channels on motility of the rat small intestine, in vivo

D. Ferens, J. Baell, G. Lessene, J. E. Smith, J. B. Furness

Journal:

Neurogastroenterology & Motility

Year:

2007

Language:

english

File:

PDF, 557 KB

english, 2007

26

Inhibition of destructive autoimmune arthritis in FcγRIIa transgenic mice by small chemical entities

Pietersz, Geoffrey A, Mottram, Patricia L, van de Velde, Nicholas C, Sardjono, Caroline Tan, Esparon, Sandra, Ramsland, Paul A, Moloney, Gerard, Baell, Jonathan B, McCarthy, Tom D, Matthews, Barry R

Journal:

Immunology & Cell Biology

Year:

2008

Language:

english

File:

PDF, 696 KB

english, 2008

27

Design and synthesis of type-III mimetics of ω-conotoxin GVIA

Jonathan B. Baell, Stewart A. Forsyth, Robert W. Gable, Raymond S. Norton, Roger J. Mulder

Journal:

Journal of Computer-Aided Molecular Design

Year:

2001

Language:

english

File:

PDF, 512 KB

english, 2001

28

Design and synthesis of type-III mimetics of ShK toxin

Jonathan B. Baell, Andrew J. Harvey, Raymond S. Norton

Journal:

Journal of Computer-Aided Molecular Design

Year:

2002

Language:

english

File:

PDF, 335 KB

english, 2002

29

Khellinone Derivatives as Blockers of the Voltage-Gated Potassium Channel Kv1.3: Synthesis and Immunosuppressive Activity

Baell, Jonathan B., Gable, Robert W., Harvey, Andrew J., Toovey, Nathan, Herzog, Tanja, Hänsel, Wolfram, Wulff, Heike

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 286 KB

english, 2004

30

Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors

Brad E. Sleebs, George Nikolakopoulos, Ian P. Street, Hendrik Falk, Jonathan B. Baell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 335 KB

english, 2011

31

Corrigendum to “Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors” [Bioorg. Med. Chem. Lett. 21 (2011) 5992–5994]

Brad E. Sleebs, George Nikolakopoulos, Ian P. Street, Hendrik Falk, Jonathan B. Baell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 225 KB

english, 2012

32

Established and Emerging Trends in Computational Drug Discovery in the Structural Genomics Era

Olivier Taboureau, Jonathan B. Baell, Juan Fernández-Recio, Bruno O. Villoutreix

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 786 KB

english, 2012

33

Redox-active nuisance screening compounds and their classification

Jonathan B. Baell

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 208 KB

english, 2011

34

Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs

Jonathan B. Baell, David C.S. Huang

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 455 KB

english, 2002

35

Phosphate Isosteres in Medicinal Chemistry

Rye, C. S., Baell, J. B.

Journal:

Current Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005

36

Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors)

Yumiko Hirokawa, Alexander Levitzki, Guillaume Lessene, Jonathan Baell, Yi Xiao, Hongjian Zhu, Hiroshi Maruta

Journal:

Year:

2007

Language:

english

File:

PDF, 295 KB

english, 2007

37

Broad Coverage of Commercially Available Lead-like Screening Space with Fewer than 350,000 Compounds

Baell, Jonathan B.

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

38

Inhibition Studies of Sulfonamide-Containing Folate Analogs in Yeast

Patel, Onisha, Satchell, Jacqueline, Baell, Jonathan, Fernley, Ross, Coloe, Peter, Macreadie, Ian

Journal:

Microbial Drug Resistance

Year:

2003

Language:

english

File:

PDF, 334 KB

english, 2003

39

Characterization of the Two Fundamental Conformations of Benzoylureas and Elucidation of the Factors That Facilitate Their Conformational Interchange

Lessene, Guillaume, Smith, Brian J., Gable, Robert W., Baell, Jonathan B.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

40

Structure-guided design of a selective BCL-XL inhibitor

Lessene, Guillaume, Czabotar, Peter E, Sleebs, Brad E, Zobel, Kerry, Lowes, Kym N, Adams, Jerry M, Baell, Jonathan B, Colman, Peter M, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Gibbons, P

Journal:

Nature Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

41

A New Class of Blockers of the Voltage-Gated Potassium Channel Kv1.3 via Modification of the 4- or 7-Position of Khellinone

Harvey, Andrew J., Baell, Jonathan B., Toovey, Nathan, Homerick, Daniel, Wulff, Heike

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 155 KB

english, 2006

42

Novel Conjugated Quinoline–Indoles Compromise Plasmodium falciparum Mitochondrial Function and Show Promising Antimalarial Activity

Teguh, Silvia C., Klonis, Nectarios, Duffy, Sandra, Lucantoni, Leonardo, Avery, Vicky M., Hutton, Craig A., Baell, Jonathan B., Tilley, Leann

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

43

LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice

Li, Rong, Doherty, Judy, Antonipillai, Juliana, Chen, Sheng, Devlin, Mark, Visser, Kathryn, Baell, Jonathan, Street, Ian, Anderson, Robin L., Bernard, Ora

Journal:

Clinical and Experimental Metastasis

Year:

2013

Language:

english

File:

PDF, 560 KB

english, 2013

44

Synthesis of conformationally constrained benzoylureas as BH3-mimetics

Brady, Ryan M., Hatzis, Effie, Connor, Theresa, Street, Ian P., Baell, Jonathan B., Lessene, Guillaume

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 504 KB

english, 2012

45

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

Dror, Ron O., Green, Hillary F., Valant, Celine, Borhani, David W., Valcourt, James R., Pan, Albert C., Arlow, Daniel H., Canals, Meritxell, Lane, J. Robert, Rahmani, Raphaël, Baell, Jonathan B., Sext

Journal:

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

46

Trypanothione Reductase High-Throughput Screening Campaign Identifies Novel Classes of Inhibitors with Antiparasitic Activity

Holloway, G. A., Charman, W. N., Fairlamb, A. H., Brun, R., Kaiser, M., Kostewicz, E., Novello, P. M., Parisot, J. P., Richardson, J., Street, I. P., Watson, K. G., Baell, J. B.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2009

Language:

english

File:

PDF, 825 KB

english, 2009

47

UNIVERSITY COLLEGE HOSPITAL.

Brady, Ryan M., Zhang, Minmin, Gable, Robert, Norton, Raymond S., Baell, Jonathan B.

Journal:

Year:

1841

Language:

english

File:

PDF, 242 KB

english, 1841

48

De novo design and synthesis of a μ-conotoxin KIIIA peptidomimetic

Brady, Ryan M., Zhang, Minmin, Gable, Robert, Norton, Raymond S., Baell, Jonathan B.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 725 KB

english, 2013

49

Structural Basis for Modulation of a GPCR by Allosteric Drugs

Dror, Ron O., Green, Hillary F., Valant, Celine, Borhani, David W., Valcourt, James R., Pan, Albert C., Arlow, Daniel H., Canals, Meritxell, Lane, J. Robert, Rahmani, Raphaël, Baell, Jonathan B., Sext

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

50

IP issues facing researchers

Almarsson, Örn, Angiolini, Mauro, Baell, Jonathan, Giardina, Giuseppe, Ingham, Andrew, Hughes, Adam, Pevarello, Paolo, Sindelar, Robert

Journal:

Pharmaceutical Patent Analyst

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

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